CYFIP1 Antikörper (C-Term)
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- Target Alle CYFIP1 Antikörper anzeigen
- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYFIP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- WAGCMIIVLL GQQRRFAVLD FCYHLLKVQK HDGKDEIIKN VPLKKMVERI
- Homologie
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYFIP1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYFIP1
- Top Product
- Discover our top product CYFIP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1253 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
- Andere Bezeichnung
- CYFIP1 (CYFIP1 Produkte)
- Synonyme
- TUBGCP5 antikoerper, P140SRA-1 antikoerper, SHYC antikoerper, SRA1 antikoerper, E030028J09Rik antikoerper, P140sra1 antikoerper, Shyc antikoerper, Sra-1 antikoerper, Sra1 antikoerper, l(7)1Rl antikoerper, l71Rl antikoerper, l7Rl1 antikoerper, mKIAA0068 antikoerper, pl-1 antikoerper, CY antikoerper, CYFIP antikoerper, fb15a06 antikoerper, wu:fb15a06 antikoerper, cytoplasmic FMR1 interacting protein 1 antikoerper, CYFIP1 antikoerper, cyfip1 antikoerper, Cyfip1 antikoerper
- Hintergrund
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CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.
Alias Symbols: FLJ45151, P140SRA-1, SHYC, SRA1
Protein Interaction Partner: EFHC2, SUMO2, MEOX1, UBC, WWOX, PRPF40A, CLUH, TCERG1, NCKAP1, ARHGEF1, GAS7, APBB1, HECW2, RFX6, EFTUD2, SCTR, PPP1CC, GNB1, UBD, MARK4, YWHAZ, YWHAH, RYK, TERF2, TERF1, CYFIP1, RAC1, FMR1, ACTA1, FXR2, FXR1, NCL,
Protein Size: 1253 - Molekulargewicht
- 145 kDa
- Gen-ID
- 23191
- NCBI Accession
- NM_014608, NP_055423
- UniProt
- Q7L576
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