MMP25 Antikörper (Middle Region)
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- Target Alle MMP25 Antikörper anzeigen
- MMP25 (Matrix Metallopeptidase 25 (MMP25))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MMP25 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FGHALGLGHS SAPNSIMRPF YQGPVGDPDK YRLSQDDRDG LQQLYGKAPQ
- Homologie
- Dog: 82%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MMP25. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product MMP25 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 562 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MMP25 (Matrix Metallopeptidase 25 (MMP25))
- Andere Bezeichnung
- MMP25 (MMP25 Produkte)
- Synonyme
- MMP-25 antikoerper, MMP20 antikoerper, MMP20A antikoerper, MMPL1 antikoerper, MT-MMP 6 antikoerper, MT-MMP6 antikoerper, MT6-MMP antikoerper, MT6MMP antikoerper, MTMMP6 antikoerper, F730048C11Rik antikoerper, Leukolysin antikoerper, matrix metallopeptidase 25 antikoerper, MMP25 antikoerper, Mmp25 antikoerper
- Hintergrund
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
Alias Symbols: MMP20, MMP20A, MMPL1, MT-MMP6, MT6-MMP
Protein Interaction Partner: CLU, MMP2,
Protein Size: 562 - Molekulargewicht
- 48 kDa
- Gen-ID
- 64386
- NCBI Accession
- NM_022468, NP_071913
- UniProt
- Q9NPA2
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