SUCLA2 Antikörper (C-Term)

Produktnummer ABIN2789919

Produktdetails anti-SUCLA2 Antikörper

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUCLA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FDLQDWTQED ERDKDAAKAN LNYIGLDGNI GCLVNGAGLA MATMDIIKLH

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SUCLA2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 463 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SUCLA2

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Andere Bezeichnung: SUCLA2 (SUCLA2 Produkte)

Synonyme: 4930547K18Rik antikoerper, A-BETA antikoerper, MTDPS5 antikoerper, SCS-betaA antikoerper, SCS antikoerper, succinate-Coenzyme A ligase, ADP-forming, beta subunit antikoerper, succinate-CoA ligase ADP-forming beta subunit antikoerper, Sucla2 antikoerper, SUCLA2 antikoerper

Hintergrund: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
Alias Symbols: A-BETA, SCS-betaA, MTDPS5
Protein Interaction Partner: FAM9B, CMTM5, AGTRAP, ARL6IP1, SUMO2, UBC, gag-pol, MRPL12, RBM4, OXCT1, IDH3A, AGFG1, S100A16, NADK2, HPDL, NIT2, SEC22B, GRHPR, SUCLG1, SDHA, RRM1, AGO4, ICT1, PSMD14, ALAS2,
Protein Size: 463

Molekulargewicht: 45 kDa

Gen-ID: 8803

NCBI Accession: NM_003850, NP_003841

UniProt: Q9P2R7