CILP Antikörper (C-Term)
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- Target Alle CILP Antikörper anzeigen
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CILP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- YIKVKIVGPL EVNVRSRNMG GTHRQTVGKL YGIRDVRSTR DRDQPNVSAA
- Homologie
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CILP. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product CILP Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1184 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
- Andere Bezeichnung
- CILP (CILP Produkte)
- Synonyme
- CILP-1 antikoerper, HsT18872 antikoerper, 9830114D16 antikoerper, C130036G17Rik antikoerper, NTPPH antikoerper, CILP antikoerper, im:7137994 antikoerper, cartilage intermediate layer protein antikoerper, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase antikoerper, cartilage intermediate layer protein 1 antikoerper, CILP antikoerper, Cilp antikoerper, cilp antikoerper, LOC100336614 antikoerper
- Hintergrund
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Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Alias Symbols: CILP-1, HsT18872
Protein Interaction Partner: NEDD1, CDC20,
Protein Size: 1184 - Molekulargewicht
- 52 kDa
- Gen-ID
- 8483
- NCBI Accession
- NM_003613, NP_003604
- UniProt
- O75339
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