TXNRD3 Antikörper (N-Term)

Produktnummer ABIN2789948

Produktdetails anti-TXNRD3 Antikörper

Target: TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSPPGRRARL SSPGPSRSSE AREELRRHLV GLIERSRVVI FSKSYCPHST

Homologie: Human: 100%, Mouse: 86%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TXNRD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TXNRD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 643 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TXNRD3

Target: TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))

Andere Bezeichnung: TXNRD3 (TXNRD3 Produkte)

Synonyme: MGC81848 antikoerper, MGC147163 antikoerper, TGR antikoerper, TR2 antikoerper, TRXR3 antikoerper, AI196535 antikoerper, Tgr antikoerper, thioredoxin reductase 3 antikoerper, apoptosis-inducing factor 3 antikoerper, thioredoxin reductase 3 L homeolog antikoerper, TXNRD3 antikoerper, LOC413958 antikoerper, txnrd3.L antikoerper, txnrd3 antikoerper, Txnrd3 antikoerper

Hintergrund: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TGR, TR2, TRXR3
Protein Interaction Partner: UBC,
Protein Size: 643

Molekulargewicht: 70 kDa

Gen-ID: 114112

NCBI Accession: NM_052883, NP_443115

UniProt: Q86VQ6

Pathways: Cell RedoxHomeostasis