PACS1 Antikörper (C-Term)

Produktnummer ABIN2789968

Produktdetails anti-PACS1 Antikörper

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FLSKKPREKE VDSKSQVIEG ISRLICSAKQ QQTMLRVSID GVEWSDIKFF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PACS1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 366 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Andere Bezeichnung: PACS1 (PACS1 Produkte)

Synonyme: MRD17 antikoerper, AI325977 antikoerper, Pacs-1 antikoerper, phosphofurin acidic cluster sorting protein 1 antikoerper, PACS1 antikoerper, Pacs1 antikoerper

Hintergrund: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Alias Symbols: -
Protein Interaction Partner: UBC, GGA3, CSNK2A1, FGFR1OP, PPP2CA, VAMP4, CLCN7, PPP2CB, PKD2, JUN, IGF2R, FURIN, TRPV4, nef,
Protein Size: 366

Molekulargewicht: 42 kDa

Gen-ID: 55690

NCBI Accession: NM_018026

UniProt: Q6VY07