REPS2 Antikörper (C-Term)

Produktnummer ABIN2790025

Produktdetails anti-REPS2 Antikörper

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund, Schwein, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KDVLYSQPPS KPIRRKFRPE NQATENQEPS TAASGPASAA TMKPHPTVQK

Homologie: Cow: 100%, Dog: 80%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against REPS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human REPS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Andere Bezeichnung: REPS2 (REPS2 Produkte)

Synonyme: POB1 antikoerper, RALBP1 associated Eps domain containing 2 antikoerper, RALBP1 associated Eps domain containing protein 2 antikoerper, REPS2 antikoerper, Reps2 antikoerper

Hintergrund: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: EPN1, CDK1, AP2A1, GRB2, AMPH, AR, CDK5RAP2, REPS1, RALBP1, EPS15, ASAP1, ASAP2, PXN, RALB, RELA,
Protein Size: 521

Molekulargewicht: 57 kDa

Gen-ID: 9185

Pathways: EGFR Signaling Pathway