NANS Antikörper (C-Term)

Produktnummer ABIN2790121

Produktdetails anti-NANS Antikörper

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NANS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS

Homologie: Cow: 86%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NANS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 359 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NANS

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Andere Bezeichnung: NANS (NANS Produkte)

Synonyme: MGC84329 antikoerper, SAS antikoerper, N-acetylneuraminate synthase L homeolog antikoerper, N-acetylneuraminate synthase antikoerper, nans.L antikoerper, NANS antikoerper, Nans antikoerper

Hintergrund: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Alias Symbols: SAS
Protein Interaction Partner: SUMO2, UBC, NEDD8, ATG3, SMEK2, CNDP2, POLE3, DAK, NPEPPS, SLC9A3R1, RPLP2, MVD, PDIA3, GBP2, EIF4E, CKB, ASS1, BAG3, HSP90AB1, HSP90AA1, PCMT1, CRK, RAD23B, DDA1,
Protein Size: 359

Molekulargewicht: 40 kDa

Gen-ID: 54187

NCBI Accession: NM_018946, NP_061819

UniProt: Q9NR45