ARHGAP8 Antikörper (Middle Region)

Produktnummer ABIN2790172

Produktdetails anti-ARHGAP8 Antikörper

Target: ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))

Bindungsspezifität: Middle Region

Reaktivität: Pferd, Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PRPPLPTQQF GVSLQYLKDK NQGELIPPVL RFTVTYLREK GLRTEGLFRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARHGAP8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ARHGAP8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 433 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGAP8

Target: ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))

Andere Bezeichnung: ARHGAP8 (ARHGAP8 Produkte)

Synonyme: BPGAP1 antikoerper, PP610 antikoerper, 3110043J09Rik antikoerper, AU043908 antikoerper, Arhgap8 antikoerper, C030017C09Rik antikoerper, C78947 antikoerper, Protor-1 antikoerper, Protor1 antikoerper, Rho GTPase activating protein 8 antikoerper, proline rich 5 (renal) antikoerper, proline rich 5 antikoerper, ARHGAP8 antikoerper, Arhgap8 antikoerper, arhgap8 antikoerper, Prr5 antikoerper

Hintergrund: This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Alias Symbols: BPGAP1, FLJ20185, PP610
Protein Interaction Partner: UBC, SH3GL1, RHOA, CDC42, BNIP2, ARHGAP1, ARHGAP8, CTTN, RAC1,
Protein Size: 433

Molekulargewicht: 50 kDa

Gen-ID: 23779

NCBI Accession: NM_181335, NP_851852

UniProt: Q86XV6