STXBP4 Antikörper (N-Term)

Produktnummer ABIN2790280

Produktdetails anti-STXBP4 Antikörper

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STXBP4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human STXBP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 553 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STXBP4

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Andere Bezeichnung: STXBP4 (STXBP4 Produkte)

Synonyme: STXBP4 antikoerper, LOC733742 antikoerper, MGC131203 antikoerper, DKFZp468L076 antikoerper, Synip antikoerper, 6030470M02Rik antikoerper, syntaxin binding protein 4 antikoerper, syntaxin binding protein 4 L homeolog antikoerper, STXBP4 antikoerper, stxbp4 antikoerper, stxbp4.L antikoerper, Stxbp4 antikoerper

Hintergrund: STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Alias Symbols: FLJ16496, MGC149829, MGC50337, Synip
Protein Interaction Partner: KLHL42, LATS2, ATN1, UBC, Plk1, STX4,
Protein Size: 553

Molekulargewicht: 62 kDa

Gen-ID: 252983

NCBI Accession: NM_178509, NP_848604

UniProt: Q6ZWJ1