NKAP Antikörper (C-Term)

Produktnummer ABIN2790485

Produktdetails anti-NKAP Antikörper

Target: NKAP (NFKB Activating Protein (NKAP))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Hund, Saccharomyces cerevisiae, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EAVRLRKENQ IYSADEKRAL ASFNQEERRK RENKILASFR EMVYRKTKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NKAP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NKAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NKAP

Target: NKAP (NFKB Activating Protein (NKAP))

Andere Bezeichnung: NKAP (NKAP Produkte)

Synonyme: DSMA4 antikoerper, GEF720 antikoerper, Syx antikoerper, Tech antikoerper, c6orf194l antikoerper, wu:fj36d09 antikoerper, wu:fj49c09 antikoerper, 2610020O08Rik antikoerper, AA987160 antikoerper, AI849147 antikoerper, AL024236 antikoerper, 2610020o08rik antikoerper, nkap antikoerper, NKAPL antikoerper, NFKB activating protein antikoerper, pleckstrin homology and RhoGEF domain containing G5 antikoerper, NFKB activating protein S homeolog antikoerper, NKAP antikoerper, PLEKHG5 antikoerper, nkap antikoerper, Nkap antikoerper, nkap.S antikoerper

Hintergrund: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Alias Symbols: FLJ22626
Protein Interaction Partner: UBC, SRPK1, CSNK2A2, TTC14, FRA10AC1, NKAP, PRPF40A, RBMX2, DDX41, RBM39, PPIG, BUB3, PRPF3, U2AF1, PCBP2, DHX15, DHX8, CUL5, SUMO2, LUC7L2, CEP70, THAP1, FAM124A,
Protein Size: 415

Molekulargewicht: 46 kDa

Gen-ID: 79576

NCBI Accession: NM_024528, NP_078804

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, Phosphorylierungen bei SARS-CoV-2 Infektion