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IYD Antikörper (N-Term)

IYD Reaktivität: Human, Ratte, Rind (Kuh), Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2790550
  • Target Alle IYD Antikörper anzeigen
    IYD (Iodotyrosine Deiodinase (IYD))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Ratte, Rind (Kuh), Hund, Kaninchen
    Wirt
    • 11
    • 1
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 9
    • 1
    • 1
    • 1
    Dieser IYD Antikörper ist unkonjugiert
    Applikation
    • 8
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV
    Homologie
    Cow: 77%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against IYD. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human IYD
    Top Product
    Discover our top product IYD Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 247 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IYD (Iodotyrosine Deiodinase (IYD))
    Andere Bezeichnung
    IYD (IYD Produkte)
    Synonyme
    MGC85450 antikoerper, C6orf71 antikoerper, DEHAL1 antikoerper, TDH4 antikoerper, dJ422F24.1 antikoerper, 0610009A07Rik antikoerper, AI265638 antikoerper, Dehal1 antikoerper, RGD1309288 antikoerper, IYD-1 antikoerper, iodotyrosine deiodinase antikoerper, iodotyrosine deiodinase L homeolog antikoerper, IYD antikoerper, iyd.L antikoerper, iyd antikoerper, Iyd antikoerper
    Hintergrund
    This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.
    Alias Symbols: C6orf71, DEHAL1, TDH4, dJ422F24.1
    Protein Interaction Partner: TRIM69,
    Protein Size: 247
    Molekulargewicht
    27 kDa
    Gen-ID
    389434
    NCBI Accession
    NM_001164695, NP_001158167
    Pathways
    Thyroid Hormone Synthesis
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