ANAPC15 Antikörper (N-Term)

Produktnummer ABIN2790945

Produktdetails anti-ANAPC15 Antikörper

Target: ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEEDDEDDED

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against ANAPC15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ANAPC15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 121 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ANAPC15

Target: ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))

Andere Bezeichnung: ANAPC15 (ANAPC15 Produkte)

Hintergrund: ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Alias Symbols: APC15, C11orf51
Protein Interaction Partner: ANAPC4, CDC26, ANAPC1, ANAPC7, ANAPC5, ANAPC2, ANAPC10, CDC16, CDC23, CDC27, CDC20,
Protein Size: 121

Molekulargewicht: 13 kDa

Gen-ID: 25906

NCBI Accession: NM_014042, NP_054761

UniProt: P60006