PARPBP Antikörper (C-Term)

Produktnummer ABIN2790948

Produktdetails anti-PARPBP Antikörper

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Bindungsspezifität: C-Term

Reaktivität: Human, Pferd, Kaninchen, Schwein, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARPBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK

Homologie: Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PARPBP

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Andere Bezeichnung: PARPBP (PARPBP Produkte)

Hintergrund: PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect.
Protein Interaction Partner: UBC,
Protein Size: 294

Molekulargewicht: 32 kDa

Gen-ID: 55010