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EFTUD1 Antikörper (N-Term)

EFTUD1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2791005
  • Target Alle EFTUD1 Antikörper anzeigen
    EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 1
    • 1
    N-Term
    Reaktivität
    • 19
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser EFTUD1 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 14
    • 13
    • 13
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    KVLEERAERE TESQVNPNSE QGEQVYDWST GLEDTDDSHL YFSPEQGNVV
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EFTUD1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human EFTUD1
    Top Product
    Discover our top product EFTUD1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1069 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
    Andere Bezeichnung
    EFTUD1 (EFTUD1 Produkte)
    Synonyme
    FAM42A antikoerper, HsT19294 antikoerper, RIA1 antikoerper, 4932434J20Rik antikoerper, 6030468D11Rik antikoerper, AI451340 antikoerper, AU019507 antikoerper, AU022896 antikoerper, D7Ertd791e antikoerper, elongation factor like GTPase 1 antikoerper, elongation factor like GPTase 1 antikoerper, EFL1 antikoerper, Efl1 antikoerper
    Hintergrund
    EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
    Alias Symbols: FAM42A, HsT19294, RIA1
    Protein Interaction Partner: TP53RK, FKBP10, RPRD1B, OSGEP, PANK4, NSUN2, UFM1, KIAA1279, ACTR2, TPD52L2, RANGAP1, LPP, BAG1, UBC,
    Protein Size: 1069
    Molekulargewicht
    117 kDa
    Gen-ID
    79631
    NCBI Accession
    NM_001040610, NP_001035700
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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