HIST1H2AE Antikörper (N-Term)

Produktnummer ABIN2791579

Produktdetails anti-HIST1H2AE Antikörper

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Ratte, Maus, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST1H2AE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GKQGGKARAK AKTRSSRAGL QFPVGRVHRL LRKGNYSERV GAGAPVYLAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST1H2AE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H2AE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Andere Bezeichnung: HIST1H2AE (HIST1H2AE Produkte)

Synonyme: H2A.1 antikoerper, H2A.2 antikoerper, H2A/a antikoerper, H2AFA antikoerper, histone cluster 1 H2A family member e antikoerper, HIST1H2AE antikoerper

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H2A.1, H2A.2, H2A/a, H2AFA
Protein Interaction Partner: UBC, HUWE1, SUZ12, EZH2, ITGA4, CAND1, COPS5, CUL1, CUL4A, CUL4B, CUL5, NFX1, NEDD8, TONSL, SUMO1, EID1, UHRF1, NAP1L4,
Protein Size: 130

Molekulargewicht: 14 kDa

Gen-ID: 3012

NCBI Accession: NM_021052, NP_066390

UniProt: P04908

Pathways: Telomere Maintenance