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NSMCE4A Antikörper (C-Term)
NSMCE4A
Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio)
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2791705
Produktdetails anti-NSMCE4A Antikörper
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Target
Alle NSMCE4A Antikörper anzeigen
NSMCE4A
(Non-SMC Element 4 Homolog A (NSMCE4A))
Bindungsspezifität
Alle Epitope für NSMCE4A Antikörper
C-Term
Reaktivität
Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio)
Wirt
Alle Wirte für NSMCE4A Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für NSMCE4A Antikörper
Polyklonal
Konjugat
Alle Konjugate für NSMCE4A Antikörper
Dieser NSMCE4A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für NSMCE4A Antikörper
Western Blotting (WB), Immunofluorescence (IF)
Sequenz
PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale
This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
Top Product
Discover our top product NSMCE4A Primärantikörper
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu NSMCE4A
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Target
NSMCE4A
(Non-SMC Element 4 Homolog A (NSMCE4A))
Andere Bezeichnung
NSMCE4A (NSMCE4A Produkte )
Synonyme
2410003A14Rik antikoerper, RGD1309025 antikoerper, C10orf86 antikoerper, NS4EA antikoerper, NSE4A antikoerper, NSE4 homolog A, SMC5-SMC6 complex component antikoerper, Nsmce4a antikoerper, NSMCE4A antikoerper
Hintergrund
NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus. Alias Symbols: C10orf86, NS4EA, NSE4A Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6, Protein Size: 385
Molekulargewicht
44 kDa
Gen-ID
54780
NCBI Accession
NM_017615 , NP_060085
UniProt
Q9NXX6
Pathways
Positive Regulation of Response to DNA Damage Stimulus
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