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NSMCE4A Antikörper (C-Term)

NSMCE4A Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio) WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2791705
  • Target Alle NSMCE4A Antikörper anzeigen
    NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio)
    Wirt
    • 17
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NSMCE4A Antikörper ist unkonjugiert
    Applikation
    • 17
    • 12
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
    Top Product
    Discover our top product NSMCE4A Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
    Andere Bezeichnung
    NSMCE4A (NSMCE4A Produkte)
    Synonyme
    2410003A14Rik antikoerper, RGD1309025 antikoerper, C10orf86 antikoerper, NS4EA antikoerper, NSE4A antikoerper, NSE4 homolog A, SMC5-SMC6 complex component antikoerper, Nsmce4a antikoerper, NSMCE4A antikoerper
    Hintergrund
    NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
    Alias Symbols: C10orf86, NS4EA, NSE4A
    Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6,
    Protein Size: 385
    Molekulargewicht
    44 kDa
    Gen-ID
    54780
    NCBI Accession
    NM_017615, NP_060085
    UniProt
    Q9NXX6
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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