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PREX2 Antikörper (N-Term)

DEPDC2 Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2791874
  • Target Alle PREX2 (DEPDC2) Antikörper anzeigen
    PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))
    Bindungsspezifität
    • 6
    • 2
    • 2
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd
    Wirt
    • 11
    • 2
    Kaninchen
    Klonalität
    • 13
    Polyklonal
    Konjugat
    • 7
    • 3
    • 2
    • 1
    Dieser PREX2 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 8
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    ERDYVGTLEF LVSAFLHRMN QCAASKVDKN VTEETVKMLF SNIEDILAVH
    Homologie
    Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PREX2. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2
    Top Product
    Discover our top product DEPDC2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))
    Andere Bezeichnung
    PREX2 (DEPDC2 Produkte)
    Synonyme
    6230420N16Rik antikoerper, DEP.2 antikoerper, DEPDC2 antikoerper, P-REX2 antikoerper, AI316880 antikoerper, AI553603 antikoerper, C030045D06Rik antikoerper, D430013K02 antikoerper, Depdc2 antikoerper, P-Rex2 antikoerper, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 antikoerper, PREX2 antikoerper, Prex2 antikoerper
    Hintergrund
    PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
    Protein Interaction Partner: PPP1CA, MTOR, TGFBR1,
    Protein Size: 1606
    Molekulargewicht
    182 kDa
    Gen-ID
    80243
    UniProt
    Q70Z35
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