SLX1A/GIYD2 Antikörper (N-Term)

Produktnummer ABIN2791914

Produktdetails anti-SLX1A/GIYD2 Antikörper

Target: SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Pferd, Meerschweinchen, Kaninchen, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLX1A/GIYD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FFGVYLLYCL NPRYRGRVYV GFTVNTARRV QQHNGGRKKG GAWRTSGRGP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLX1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SLX1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SLX1A/GIYD2

Target: SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))

Andere Bezeichnung: SLX1B (SLX1B Produkte)

Synonyme: 1110030E23Rik antikoerper, 2410170E21Rik antikoerper, 4833422P03Rik antikoerper, AI853643 antikoerper, Giyd1 antikoerper, Giyd2 antikoerper, LRRGT00058 antikoerper, RGD1311568 antikoerper, GIYD2 antikoerper, SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) antikoerper, SLX1 homolog B, structure-specific endonuclease subunit antikoerper, Slx1b antikoerper, SLX1B antikoerper

Hintergrund: This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication, this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
Protein Interaction Partner: SLX4, THAP11, DUSP10, TUBA1B, LOC344382, EME1, SLX4IP, SLIRP, MUS81, GEMIN6, PAGR1, FKBP10, GEMIN4, DDX20, TIMM17B, PSME3, SLC25A13, HUWE1, PSMD6, CUL1, UQCRC2, SMN1, S100A8, RAN, PSMD11, PSMB5, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA
Protein Size: 275

Molekulargewicht: 30 kDa

Gen-ID: 79008

UniProt: Q9BQ83

Pathways: DNA Reparatur