ASCL1 Antikörper (Middle Region)
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- Target Alle ASCL1 Antikörper anzeigen
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ASCL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- AGVLSPTISP NYSNDLNSMA GSPVSSYSSD EGSYDPLSPE EQELLDFTNW
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ASCL1
- Top Product
- Discover our top product ASCL1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 236 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- Andere Bezeichnung
- ASCL1 (ASCL1 Produkte)
- Synonyme
- ASH1 antikoerper, HASH1 antikoerper, MASH1 antikoerper, bHLHa46 antikoerper, AI225900 antikoerper, Mash1 antikoerper, ASCL1 antikoerper, Zash-1a antikoerper, ash antikoerper, asha antikoerper, id:ibd5085 antikoerper, im:7138587 antikoerper, si:dkey-264k15.2 antikoerper, zash1a antikoerper, zasha antikoerper, Xash1 antikoerper, ascl1-A antikoerper, Zash-1b antikoerper, ashb antikoerper, zashb antikoerper, achaete-scute family bHLH transcription factor 1 antikoerper, achaete-scute family bHLH transcription factor 1a antikoerper, achaete-scute family bHLH transcription factor 1 L homeolog antikoerper, achaete-scute complex homolog 1 antikoerper, achaete-scute family bHLH transcription factor 1b antikoerper, ASCL1 antikoerper, Ascl1 antikoerper, ascl1a antikoerper, ascl1.L antikoerper, LOC100220505 antikoerper, ascl1b antikoerper
- Hintergrund
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ASCL1 may play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. ASCL1 is essential for the generation of olfactory and autonomic neurons. ASCL1 activates transcription by binding to the E box (5'-CANNTG-3').This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ASH1, HASH1, MASH1, bHLHa46
Protein Interaction Partner: MEF2D, MEF2C, MEF2A, NEUROG2, UBQLN1, EP300, TCF4, BMP2, ASCL1,
Protein Size: 236 - Molekulargewicht
- 25 kDa
- Gen-ID
- 429
- NCBI Accession
- NM_004316, NP_004307
- UniProt
- P50553
- Pathways
- Dopaminergic Neurogenesis
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