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YWHAE Antikörper (Middle Region)

YWHAE Reaktivität: Maus, Zebrafisch (Danio rerio), Meerschweinchen, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2792142
  • Target Alle YWHAE Antikörper anzeigen
    YWHAE (14-3-3 epsilon (YWHAE))
    Bindungsspezifität
    • 15
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 57
    • 42
    • 39
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus, Zebrafisch (Danio rerio), Meerschweinchen, Hund
    Wirt
    • 53
    • 4
    • 1
    Kaninchen
    Klonalität
    • 47
    • 11
    Polyklonal
    Konjugat
    • 27
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser YWHAE Antikörper ist unkonjugiert
    Applikation
    • 41
    • 16
    • 13
    • 13
    • 12
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    ELDTLSEESY KDSTLIMQLL RDNLTLWTSD MQGDGEEQNK EALQDVEDEN
    Homologie
    Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against YWHAE. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human YWHAE
    Top Product
    Discover our top product YWHAE Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 255 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tak, Jang, Kim, Park, Suk, Yoon, Ahn, Lee, Joe: "14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization." in: Cellular signalling, Vol. 19, Issue 11, pp. 2379-87, (2007) (PubMed).

  • Target
    YWHAE (14-3-3 epsilon (YWHAE))
    Andere Bezeichnung
    YWHAE (YWHAE Produkte)
    Synonyme
    14-3-3 antikoerper, 14-3-3 epsilon antikoerper, 14-3-3-e antikoerper, 14-3-3-epsilon antikoerper, 14-3-30epsilon antikoerper, 14-3-3EPSILON antikoerper, 14-3-3e antikoerper, 14-3-3omicron antikoerper, 1433epsilon antikoerper, 143E_DROME antikoerper, CG31196 antikoerper, CT24092 antikoerper, D14-3-3e antikoerper, D14-3-3epsilon antikoerper, Dmel\\CG31196 antikoerper, EK3-5 antikoerper, PAR-5 antikoerper, PAR5 antikoerper, Par-5 antikoerper, SR3-9 antikoerper, Su(Raf)3B antikoerper, anon-WO0172774.141 antikoerper, anon-WO02059370.52 antikoerper, d14-3-3epsilon antikoerper, eps antikoerper, l(3)j2B10 antikoerper, par-5 antikoerper, 14-3-3epsilon antikoerper, kcip-1 antikoerper, mdcr antikoerper, mds antikoerper, LOC581376 antikoerper, Ywhae antikoerper, ACYPI002517 antikoerper, YWHAE antikoerper, 14-3-3E antikoerper, KCIP-1 antikoerper, MDCR antikoerper, MDS antikoerper, AU019196 antikoerper, fe38c12 antikoerper, wu:fb48f06 antikoerper, wu:fe38c12 antikoerper, wu:fi22e10 antikoerper, ywhae antikoerper, zgc:55377 antikoerper, zgc:77062 antikoerper, CG31196 gene product from transcript CG31196-RD antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon antikoerper, 14-3-3 epsilon antikoerper, 14-3-3 epsilon protein antikoerper, 14-3-3 protein epsilon antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 antikoerper, 14-3-3epsilon antikoerper, ywhae antikoerper, LOC581376 antikoerper, Ywhae antikoerper, HCAG_04173 antikoerper, PTRG_02836 antikoerper, PTRG_04459 antikoerper, UREG_07864 antikoerper, YWHAE antikoerper, ywhae.S antikoerper, ywhae1 antikoerper
    Hintergrund
    YWHAE is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAE binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. The binding generally results in the modulation of the activity of the binding partner.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: 14-3-3E, FLJ45465, KCIP-1, MDCR, MDS
    Protein Interaction Partner: DTL, HUWE1, FAM53C, FBXW11, SORBS2, UBC, ABL1, GRB10, SIK2, CEP57, SIK3, TP53, IRS4, CBL, TUBB2A, TWF2, PROSC, FERMT2, PDIA4, RAP1GDS1, PTMA, PPP1R2, PDHB, PAK2, PAFAH1B2, YWHAH, XPO1, VCL, GSS, G6PD, EIF5, TBCB, CAPNS1, CAPN2, ALDH7A1, ATIC, ASNS, SCPEP1
    Protein Size: 255
    Molekulargewicht
    29 kDa
    Gen-ID
    7531
    NCBI Accession
    NM_006761, NP_006752
    UniProt
    P62258
    Pathways
    Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase
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