CDC25A Antikörper (Middle Region)
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- Target Alle CDC25A Antikörper anzeigen
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDC25A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MELCEPQSYC PMHHQDHKTE LLRCRSQSKV QEGERQLREQ IALLVKDMSP
- Homologie
- Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CDC25A. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CDC25A
- Top Product
- Discover our top product CDC25A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 484 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- Andere Bezeichnung
- CDC25A (CDC25A Produkte)
- Synonyme
- cdc25a2 antikoerper, cdc25A antikoerper, sb:cb317 antikoerper, CDC25A2 antikoerper, D9Ertd393e antikoerper, cell division cycle 25A antikoerper, cell division cycle 25B antikoerper, cell division cycle 25A S homeolog antikoerper, CDC25A antikoerper, cdc25a antikoerper, cdc25b antikoerper, Cdc25a antikoerper, cdc25a.S antikoerper
- Hintergrund
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CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CDC25A2
Protein Interaction Partner: ANAPC11, FZR1, FBXW11, BTRC, CUL1, SKP1, VCP, UBC, NPLOC4, YWHAQ, SCYL1, CAMK1D, POLR1D, FGF21, CHEK2, CCNI, MCM3AP, VAMP8, CUL3, XPO1, SOX5, PEX19, NFYA, NFKBIB, MTAP, SMAD3, LMO2, IL3RA, HLA-C, FTH1, EEF1A1, DMD, CHEK1, APP, TRIB3, CSNK1A1, CDK2, FAM193
Protein Size: 484 - Molekulargewicht
- 54 kDa
- Gen-ID
- 993
- NCBI Accession
- NM_201567, NP_963861
- UniProt
- P30304
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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