DP1 Antikörper (Middle Region)

Produktnummer ABIN2792234

Produktdetails anti-DP1 Antikörper

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SASDLTNGAD GMLATSSNGS QYSGSRVETP VSYVGEDDEE DDDFNENDED

Homologie: Cow: 92%, Human: 100%, Mouse: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TFDP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFDP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 410 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DP1

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Andere Bezeichnung: TFDP1 (TFDP1 Produkte)

Hintergrund: The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells. The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors, see TFDP2 (MIM 602160).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DP1, DRTF1, Dp-1
Protein Interaction Partner: UBC, E2F6, E2F4, SIAH1, E2F3, E2F2, E2F1, CDK6, PRPF31, CDK2, CDK1, SOCS3, RB1, PCGF6, RYBP, YAF2, RNF2, ELAVL1, LIN9, LIN54, LIN37, RBL2, SERTAD2, NPDC1, E2F5, TP53, RBL1, CDK3, TP53BP1,
Protein Size: 410

Molekulargewicht: 45 kDa

Gen-ID: 7027

NCBI Accession: NM_007111, NP_009042

UniProt: Q14186

Pathways: Zellzyklus, Mitotic G1-G1/S Phases