CCR8 Antikörper (Middle Region)
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- Target Alle CCR8 Antikörper anzeigen
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Rind (Kuh), Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CCR8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MATIPLLVFY QVASEDGVLQ CYSFYNQQTL KWKIFTNFKM NILGLLIPFT
- Homologie
- Cow: 93%, Human: 100%, Rabbit: 81%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CCR8. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CCR8
- Top Product
- Discover our top product CCR8 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 355 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
- Andere Bezeichnung
- CCR8 (CCR8 Produkte)
- Hintergrund
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CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.
Alias Symbols: CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8
Protein Interaction Partner: TPST2, TPST1, CCR8, CCL17, CCL16, CCL4, CCL1,
Protein Size: 355 - Molekulargewicht
- 41 kDa
- Gen-ID
- 1237
- NCBI Accession
- NM_005201, NP_005192
- UniProt
- P51685
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