CHRNA9 Antikörper (N-Term)

Produktnummer ABIN2792251

Produktdetails anti-CHRNA9 Antikörper

Target: CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))

Bindungsspezifität: N-Term

Reaktivität: Maus, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MNWSHSCISF CWIYFAASRL RAAETADGKY AQKLFNDLFE DYSNALRPVE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 93%, Rabbit: 100%, Zebrafish: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against CHRNA9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA9

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 479 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CHRNA9 Antikörper (ABIN2792251)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Details zu CHRNA9

Target: CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))

Andere Bezeichnung: CHRNA9 (CHRNA9 Produkte)

Synonyme: HSA243342 antikoerper, NACHRA9 antikoerper, 2410015I05Rik antikoerper, Acra9 antikoerper, EG666827 antikoerper, Gm8311 antikoerper, cholinergic receptor nicotinic alpha 9 subunit antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 9 antikoerper, CHRNA9 antikoerper, Chrna9 antikoerper

Hintergrund: CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
Alias Symbols: NACHRA9, HSA243342
Protein Interaction Partner: UBC, Rapsn,
Protein Size: 479

Molekulargewicht: 55 kDa

Gen-ID: 55584

NCBI Accession: NM_017581, NP_060051

UniProt: Q9UGM1

Pathways: Sensory Perception of Sound