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VEGFR2/CD309 Antikörper (N-Term)

Name: VEGFR2/CD309 Antikörper (N-Term)
SKU: ABIN2792307
Price: 534.11 EUR
Availability: InStock

VEGFR2 Reaktivität: Human, Schwein, Hund, Pferd, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-KDR Antibody Titration: 0. (VEGFR2/CD309 Antikörper (N-Term))

Image no. 1 for anti-VEGF Receptor 2 (VEGFR2) (N-Term) antibody (ABIN2792307) (VEGFR2/CD309 Antikörper (N-Term))

Researcher: Department of Pathology, Hospital de Carabineros de Chile, Santiago, ChileApplication: IHCSpecies+tissue/cell type: Control-Human Placenta, Sample-Human colorectal cancer Primary Antibody dilution: 1:100Secondary Antibody: Biotinylated pig anti-rabbit+streptavidin-HRP (VEGFR2/CD309 Antikörper (N-Term))

IHC

KDR in endothelial cells in blood vessels in placenta was detected using HRP/AEC red color stain. (VEGFR2/CD309 Antikörper (N-Term))

IHC

4 Abbildungen

Produktnummer ABIN2792307

Datenblatt (PDF)

Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Bindungsspezifität
37

34

27

23

20

16

11

10

10

10

8

6

5

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
285

182

124

8

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Human, Schwein, Hund, Pferd, Rind (Kuh)
Wirt
266

58

23

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
258

91
Polyklonal
Konjugat
158

29

17

12

10

9

9

7

7

7

7

6

5

5

5

5

5

5

5

5

5

5

5

3

2

2

2

1

1

1

1

1

1

1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
Applikation
208

112

92

78

62

24

22

18

13

13

11

9

7

7

7

4

2

2

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz

LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD

Homologie

Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%

Produktmerkmale

This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KDR

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Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 1356 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung

KDR (VEGFR2 Produkte)

Hintergrund

KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Alias Symbols: CD309, FLK1, VEGFR, VEGFR2
Protein Interaction Partner: FBXO25, VEGFA, MYO1C, CAV1, NPM1, EPN1, SRC, CBL, IQGAP1, UBC, CSNK1D, FBXW11, BTRC, CUL1, AIMP2, SHC2, SYNGAP1, ACP1, ATR, FRS2, SH2D2A, DNM2, NRP1, VEGFC, GRB10, CDH5, GNAQ, SHC1, STAT1, NCK1, SHB, PLCG2, P2RY2, BMX, FIGF, KDR, TIMP3, PTPN6, PTPN11, ITG
Protein Size: 1356

Molekulargewicht

151 kDa

Gen-ID

3791

NCBI Accession

NM_002253, NP_002244

UniProt

P35968

Pathways

RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling