NFYC Antikörper (C-Term)

Produktnummer ABIN2792552

Produktdetails anti-NFYC Antikörper

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFYC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MTSLSPLHPS QQLYQIQQVT MPAGQDLAQP MFIQSANQPS DGQAPQVTGD

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against NFYC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYC

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-NFYC Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFYC

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Andere Bezeichnung: NFYC (NFYC Produkte)

Synonyme: CBF-C antikoerper, CBFC antikoerper, H1TF2A antikoerper, HAP5 antikoerper, HSM antikoerper, NF-YC antikoerper, fb98f01 antikoerper, wu:fb98f01 antikoerper, zgc:55514 antikoerper, cbf-c antikoerper, cbfc antikoerper, h1tf2a antikoerper, hap5 antikoerper, hsm antikoerper, nf-yc antikoerper, NFYC antikoerper, Nfyc antikoerper, nuclear transcription factor Y subunit gamma antikoerper, nuclear transcription factor Y, gamma antikoerper, nuclear transcription factor Y subunit gamma L homeolog antikoerper, nuclear transcription factor-Y gamma antikoerper, nuclear Y/CCAAT-box binding factor C subunit NF-YC antikoerper, NFYC antikoerper, nfyc antikoerper, nfyc.L antikoerper, Nfyc antikoerper

Hintergrund: NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.
Alias Symbols: HSM, CBFC, HAP5, CBF-C, NF-YC, H1TF2A
Protein Interaction Partner: NFYA, CDK2, UBC, SNX2, NFYB, Cebpb, ELAVL1, GAPDH, KAT2B, TP73, TAF12, TAF11, TAF6, TBPL2, TRIM27, HDAC1, KIAA2018, ARID2, GLTSCR1, GLTSCR1L, ZDHHC17, CIC, POGZ, ATF6, ADNP2, LMO4, SREBF2, SP1, DR1, CSN2, DST, SMAD3, SMAD2, ATF6B, MYC, TBP,
Protein Size: 458

Molekulargewicht: 50 kDa

Gen-ID: 4802

NCBI Accession: NM_001142587

UniProt: Q13952

Pathways: Regulation of Lipid Metabolism by PPARalpha