HOXA10 Antikörper (N-Term)

Produktnummer ABIN2792574

Produktdetails anti-HOXA10 Antikörper

Target: HOXA10 (Homeobox A10 (HOXA10))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MSCSESPAAN SFLVDSLISS GRGEAGGGGG GAGGGGGGGY YAHGGVYLPP

Kreuzreaktivität: Human, Maus, Kaninchen, Ratte (Rattus)

Homologie: Dog: 85%, Human: 92%, Mouse: 78%, Rabbit: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXA10. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA10

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-HOXA10 Antibody Titration: 1.25 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 393 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXA10 Antikörper (ABIN2792574)

Ko, Lengyel, Naora: "The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions." in: Molecular and cellular endocrinology, Vol. 317, Issue 1-2, pp. 112-9, (2010) (PubMed).

Details zu HOXA10

Target: HOXA10 (Homeobox A10 (HOXA10))

Andere Bezeichnung: HOXA10 / HOX1H (HOXA10 Produkte)

Hintergrund: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA10 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment.
Alias Symbols: PL, HOX1, HOX1H, HOX1.8
Protein Interaction Partner: SPI1, COPS5, CREBBP, PBX1, SNAPC1, EMX1, POLR3D, SIRT2, GMNN, EP300, MEIS1, PTPN6, HOXA10, FOXO1,
Protein Size: 393

Molekulargewicht: 41 kDa

Gen-ID: 3206

NCBI Accession: NM_018951, NP_061824

UniProt: P31260