POU3F2 Antikörper (C-Term)

Produktnummer ABIN184321

Produktdetails anti-POU3F2 Antikörper

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU3F2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QLEKEVVRVW FCNRRQKEKR MTPPGGTLPG AEDVYGGSRD TPPHHGVQTP

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Human: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against POU3F2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human POU3F2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-POU3F2 Antibody Titration: 0.2-1 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 443 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POU3F2

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Andere Bezeichnung: POU3F2 (POU3F2 Produkte)

Hintergrund: N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1, MIM 164175) and Oct2 (POU2F2, MIM 164176), and the pituitary protein Pit1 (PIT1, MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Alias Symbols: BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7
Protein Interaction Partner: UBC, TBP, SOX10, POU3F2, PAX3, GTF2B, EP300, SOX11, PQBP1, POU3F4,
Protein Size: 443

Molekulargewicht: 47 kDa

Gen-ID: 5454

NCBI Accession: NM_005604, NP_005595

UniProt: P20265