NFATC3 Antikörper (N-Term)
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- Target Alle NFATC3 Antikörper anzeigen
- NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFATC3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- AVFPFQYCVE TDIPLKTRKT SEDQAAILPG KLELCSDDQG SLSPARETSI
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NFATC3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC3
- Top Product
- Discover our top product NFATC3 Primärantikörper
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- Applikationshinweise
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WB Suggested Anti-NFATC3 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Hela cell lysate.
Immunohistochemistry with Thymus tissue at an antibody concentration of 5 µg/mL using anti-NFATC3 antibody (ABIN504679).
Optimal working dilutions should be determined experimentally by the investigator. - Kommentare
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Antigen size: 1068 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))
- Andere Bezeichnung
- NFAT4 / NFATC3 (NFATC3 Produkte)
- Synonyme
- NFATC3 antikoerper, NFATx antikoerper, nf-at antikoerper, nfat4 antikoerper, nfatx antikoerper, C80703 antikoerper, D8Ertd281e antikoerper, NFAT4 antikoerper, NFATX antikoerper, nuclear factor of activated T-cells 3 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 antikoerper, nuclear factor of activated T-cells 3 S homeolog antikoerper, NFATC3 antikoerper, nfatc3 antikoerper, Nfatc3 antikoerper, nfatc3.S antikoerper
- Hintergrund
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NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. NFATC3 plays a role in the regulation of gene expression in T cells and immature thymocytes.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: NFAT4, NFATX
Protein Interaction Partner: MAPK9, MAPK8, CDK6, NCOA3, TTF1, CSNK1A1, FOS,
Protein Size: 1068 - Molekulargewicht
- 115 kDa
- Gen-ID
- 4775
- NCBI Accession
- NM_004555, NP_004546
- UniProt
- B5B2S0
- Pathways
- RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Chromatin Binding
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