GTF2B Antikörper (N-Term)

Produktnummer ABIN2792692

Produktdetails anti-GTF2B Antikörper

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Hund, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NLPRNIVDRT NNLFKQVYEQ KSLKGRANDA IASACLYIAC RQEGVPRTFK

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-GTF2B Antibody Titration: 4.0 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 316 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GTF2B Antikörper (ABIN2792692)

Tubon, Tansey, Herr: "A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2863-74, (2004) (PubMed).

Details zu GTF2B

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Andere Bezeichnung: GTF2B (GTF2B Produkte)

Synonyme: CG5193 antikoerper, Dmel\\CG5193 antikoerper, TFIIB antikoerper, Tfiib antikoerper, TfllB antikoerper, dTFIIB antikoerper, dTfIIB antikoerper, dmTFIIB antikoerper, gtf2b antikoerper, tf2b antikoerper, tfiib antikoerper, XLTFIIB antikoerper, TF2B antikoerper, wu:fc44c11 antikoerper, zgc:66258 antikoerper, Transcription factor IIB antikoerper, transcription initiation factor iib antikoerper, transcription initiation factor IIB antikoerper, transcription initiation factor IIB 2 antikoerper, Transcription initiation factor IIB antikoerper, general transcription factor 2B S homeolog antikoerper, general transcription factor 2B L homeolog antikoerper, general transcription factor IIB antikoerper, TfIIB antikoerper, CNF01950 antikoerper, tfb antikoerper, CC1G_14689 antikoerper, HacjB3_18813 antikoerper, HALXA_RS07110 antikoerper, HALXA_RS16310 antikoerper, tf2b antikoerper, LOC100283348 antikoerper, gtf2b.S antikoerper, gtf2b.L antikoerper, GTF2B antikoerper, gtf2b antikoerper, Gtf2b antikoerper

Hintergrund: GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: DRAP1, TNIP1, UBC, FBXO25, HNF4A, TCEA1, GTF2F2, GTF2F1, DEPDC7, SLC22A2, RELA, POLR2C, JAK3, HMGCL, SMURF1, THRA, TBP, POLR2E, SRA1, LSM4, LSM5, CIITA, NXF1, POU3F2, EP300, PSMA3, POLR2J, ESR1, UL48, NR1D2, NCOR1, TAF9, REST, tat, SAP25, MKX, CTDP1, POLR
Protein Size: 316

Molekulargewicht: 35 kDa

Gen-ID: 2959

NCBI Accession: NM_001514, NP_001505

UniProt: Q00403