CFLA Antikörper (Center)

Produktnummer ABIN2793618

Produktdetails anti-CFLA Antikörper

Target: CFLA (VVL) (POU Domain Protein CF1A (VVL))

Bindungsspezifität: AA 145-174, Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)

Verwendungszweck: Rabbit Anti-Human CFLAR (Center) Antibody

Immunogen: This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of CFLAR Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.000 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu CFLA

Target: CFLA (VVL) (POU Domain Protein CF1A (VVL))

Andere Bezeichnung: CFLA

Hintergrund:

Target Description: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.

Gene Symbol: CFLAR

Molekulargewicht: 55344 Da

Gen-ID: 8837

UniProt: O15519