HAT1 Antikörper (C-Term)

Produktnummer ABIN2797110

Produktdetails anti-HAT1 Antikörper

Target: HAT1 (Histone Aminotransferase 1 (HAT1))

Bindungsspezifität: AA 389-419, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit Anti-Human KAT1 (HAT1) (C-term) Antibody

Immunogen: This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of hHAT1-E404 was detected using the purified Pab.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu HAT1

Target: HAT1 (Histone Aminotransferase 1 (HAT1))

Andere Bezeichnung: KAT1 (HAT1 Produkte)

Synonyme: GTK antikoerper, KAT1 antikoerper, KATI antikoerper, kynurenine aminotransferase 1 antikoerper, KYAT1 antikoerper

Hintergrund:

Target Description: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

Gene Symbol: HAT1

Molekulargewicht: 49513 Da

Gen-ID: 8520

UniProt: O14929