RanBP3 Antikörper (AA 441-540) (Biotin)

Produktnummer ABIN2803269

Produktdetails anti-RanBP3 Antikörper (Biotin)

Target: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Bindungsspezifität: AA 441-540

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RanBP3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RanBP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RanBP3

Target: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Andere Bezeichnung: RanBP3 (RANBP3 Produkte)

Synonyme: 2610024N24Rik antikoerper, AA408221 antikoerper, ranbp3 antikoerper, MGC79798 antikoerper, zgc:63485 antikoerper, RAN binding protein 3 antikoerper, RAN binding protein 3 L homeolog antikoerper, RAN binding protein 3a antikoerper, RANBP3 antikoerper, Ranbp3 antikoerper, ranbp3.L antikoerper, ranbp3 antikoerper, ranbp3a antikoerper

Hintergrund:

Synonyms: Ran-binding protein 3, RanBP3

Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

Gen-ID: 8498

UniProt: Q9H6Z4