SOCS7 Antikörper (AA 171-270) (Biotin)

Produktnummer ABIN2803270

Produktdetails anti-SOCS7 Antikörper (Biotin)

Target: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Bindungsspezifität: AA 171-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS7 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOCS7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SOCS7

Target: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Andere Bezeichnung: SOCS7 (SOCS7 Produkte)

Synonyme: NAP4 antikoerper, NCKAP4 antikoerper, SOCS4 antikoerper, SOCS6 antikoerper, 2310063P06Rik antikoerper, C85125 antikoerper, Nap4 antikoerper, GB13951 antikoerper, zgc:175115 antikoerper, SOCS7 antikoerper, socs7 antikoerper, suppressor of cytokine signaling 7 antikoerper, suppressor of cytokine signaling antikoerper, SOCS7 antikoerper, Socs7 antikoerper, LOC413772 antikoerper, socs7 antikoerper

Hintergrund:

Synonyms: NAP4, NCKAP4, Suppressor of cytokine signaling 7, SOCS-7, Nck, Ash and phospholipase C gamma-binding protein, Nck-associated protein 4, NAP-4, SOCS7, SOCS6

Background: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Gen-ID: 30837

UniProt: O14512