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MYLK2 Antikörper (AbBy Fluor® 594)

MYLK2 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2804422
  • Target Alle MYLK2 Antikörper anzeigen
    MYLK2 (Myosin Light Chain Kinase 2 (MYLK2))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 27
    • 3
    Kaninchen
    Klonalität
    • 29
    • 1
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYLK2 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 24
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MYLK2
    Isotyp
    IgG
    Top Product
    Discover our top product MYLK2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MYLK2 (Myosin Light Chain Kinase 2 (MYLK2))
    Andere Bezeichnung
    MYLK2 (MYLK2 Produkte)
    Synonyme
    KMLC antikoerper, MLCK antikoerper, MLCK2 antikoerper, skMLCK antikoerper, 9830004H17Rik antikoerper, BB138278 antikoerper, Klmc antikoerper, Mlck antikoerper, myosin light chain kinase 2 antikoerper, myosin, light polypeptide kinase 2, skeletal muscle antikoerper, MYLK2 antikoerper, Mylk2 antikoerper, mylk2 antikoerper
    Hintergrund

    Synonyms: KMLC, MLCK, MLCK2, MYLK 2, Myosin light chain kinase 2, Myosin light chain kinase 2 skeletal muscle, Myosin light chain kinase 2 skeletal/cardiac muscle, Skeletal muscle myosin light chain kinase, Skeletal myosin light chain kinase, skMLCK, MYLK2_HUMAN.

    Background: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and myosin light chain kinases (MYLK, also designated MLCK). The MYLK kinases phosphorylate myosin regulatory light chains to catalyze myosin interaction with actin filaments resulting in contractile activity. Non-muscle, smooth muscle and skeletal/cardiac muscle MYLK isoforms exist. The MYLK gene (also designated MYLK1) encodes both smooth muscle and non-muscle isoforms as well as telokin, a small C-terminal isoform expressed only in smooth muscle with the capacity to stabilize unphosphorylated myosin filaments. Multiple transcript variants are described for the MYLK gene. Smooth-muscle and non-muscle MYLK isoforms are expressed in a wide variety of adult and fetal tissues. The skeletal/cardiac muscle isoforms of MYLK are encoded by a separate gene, MYLK2 (also designated skMLCK). MYLK appears to be a target for PAKs (p21-activated kinases). PAK1 interaction with MYLK results in a decrease in MYLK activity and myosin light chain phosphorylation.

    Gen-ID
    85366
    Pathways
    Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation
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