NSG1 Antikörper (AA 1-100) (AbBy Fluor® 594)
-
- Target Alle NSG1 (D4S234E) Antikörper anzeigen
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
-
Bindungsspezifität
- AA 1-100
-
Reaktivität
- Maus, Affe
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NSG1 Antikörper ist konjugiert mit AbBy Fluor® 594
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Affe, Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NEEP21
- Isotyp
- IgG
- Top Product
- Discover our top product D4S234E Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
- Andere Bezeichnung
- NEEP21 (D4S234E Produkte)
- Synonyme
- D4S234 antikoerper, D4S234E antikoerper, NEEP21 antikoerper, P21 antikoerper, Neep21 antikoerper, m234 antikoerper, p21 antikoerper, Bsmrb antikoerper, PEP1 antikoerper, neuronal vesicle trafficking associated 1 antikoerper, neuron specific gene family member 1 antikoerper, NSG1 antikoerper, Nsg1 antikoerper
- Hintergrund
-
Synonyms: neuron-enriched endosomal 21 kDa protein, NSG1_HUMAN.
Background: NEEP21, also known as Brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).
-