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PLSCR3 Antikörper (AA 201-295) (AbBy Fluor® 594)

PLSCR3 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2805444
  • Target Alle PLSCR3 Antikörper anzeigen
    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
    Bindungsspezifität
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-295
    Reaktivität
    • 26
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 23
    • 5
    Kaninchen
    Klonalität
    • 23
    • 5
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PLSCR3 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 13
    • 12
    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PLSCR3
    Isotyp
    IgG
    Top Product
    Discover our top product PLSCR3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
    Andere Bezeichnung
    PLSCR3 (PLSCR3 Produkte)
    Synonyme
    2210403O21Rik antikoerper, 2610037N06Rik antikoerper, ESTM3 antikoerper, X83310 antikoerper, Pls3 antikoerper, zgc:77051 antikoerper, phospholipid scramblase 3 antikoerper, phospholipid scramblase 3b antikoerper, PLSCR3 antikoerper, Plscr3 antikoerper, plscr3b antikoerper
    Hintergrund

    Synonyms: Ca2+-dependent phospholipid scramblase 3, Phospholipid scramblase 3, PL scramblase 3, PLS3, PLS3_HUMAN.

    Background: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

    Gen-ID
    57048
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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