SHoc2/Sur8 Antikörper (AA 36-120) (AbBy Fluor® 594)
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- Target Alle SHoc2/Sur8 (SHOC2) Antikörper anzeigen
- SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
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Bindungsspezifität
- AA 36-120
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SHoc2/Sur8 Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SHOC2/Sur8
- Isotyp
- IgG
- Top Product
- Discover our top product SHOC2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
- Andere Bezeichnung
- SHOC2 (SHOC2 Produkte)
- Synonyme
- AU017287 antikoerper, Sur8 antikoerper, mKIAA0862 antikoerper, SIAA0862 antikoerper, SOC2 antikoerper, SUR8 antikoerper, si:ch211-159c12.3 antikoerper, si:ch211-197i12.3 antikoerper, zgc:152956 antikoerper, soc-2 (suppressor of clear) homolog (C. elegans) antikoerper, SHOC2 leucine-rich repeat scaffold protein antikoerper, SHOC2 leucine-rich repeat scaffold protein S homeolog antikoerper, SHOC2, leucine rich repeat scaffold protein antikoerper, Shoc2 antikoerper, shoc2.S antikoerper, SHOC2 antikoerper, shoc2 antikoerper
- Hintergrund
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Synonyms: Leucine-rich repeat protein SHOC-2, Leucine-rich repeat protein SHOC-2, Ras-binding protein Sur-8, KIAA0862, Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein Sur-8 homolog, SHOC2, SHOC2_HUMAN.
Background: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.
- Gen-ID
- 8036
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