TANK Antikörper (AA 151-260) (AbBy Fluor® 594)
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- Target Alle TANK Antikörper anzeigen
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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Bindungsspezifität
- AA 151-260
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TANK Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TANK
- Isotyp
- IgG
- Top Product
- Discover our top product TANK Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Andere Bezeichnung
- TANK (TANK Produkte)
- Synonyme
- I-TRAF antikoerper, ITRAF antikoerper, TRAF2 antikoerper, C86182 antikoerper, E430026L09Rik antikoerper, zgc:153048 antikoerper, i-traf antikoerper, tank antikoerper, traf2 antikoerper, TRAF family member associated NFKB activator antikoerper, TRAF family member-associated Nf-kappa B activator antikoerper, TRAF family member-associated NFKB activator antikoerper, TRAF family member associated NFKB activator L homeolog antikoerper, TANK antikoerper, Tank antikoerper, tank antikoerper, tank.L antikoerper
- Hintergrund
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Synonyms: I TRAF, ITRAF, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF interacting protein, TRAF interacting protein TANK isoform a, I-TRAF, Tank, TANK_HUMAN, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF interacting protein TANK isoform b, TRAF2.
Background: TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, this protein can block TRAF2 binding to LMP1, the Epstein Barr virus transforming protein, and inhibit LMP1-mediated NF kappa B activation.
- Gen-ID
- 10010
- Pathways
- p53 Signalweg, TLR Signalweg, Activation of Innate immune Response
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