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UBE2E2 Antikörper (AA 1-100) (AbBy Fluor® 594)

UBE2E2 Reaktivität: Human, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2807342
  • Target Alle UBE2E2 Antikörper anzeigen
    UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 6
    • 2
    • 2
    • 2
    AA 1-100
    Reaktivität
    • 46
    • 21
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 45
    • 1
    Polyklonal
    Konjugat
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2E2 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 40
    • 18
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UBE2E2
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))
    Andere Bezeichnung
    UBE2E2 (UBE2E2 Produkte)
    Synonyme
    ubch8 antikoerper, UBCH8 antikoerper, wu:fb38h07 antikoerper, zgc:92467 antikoerper, BC016265 antikoerper, ubiquitin-conjugating enzyme E2E 2 antikoerper, ubiquitin conjugating enzyme E2E 2 L homeolog antikoerper, ubiquitin conjugating enzyme E2E 2 antikoerper, Ube2e2 protein antikoerper, ubiquitin conjugating enzyme E2 E2 antikoerper, UBE2E2 antikoerper, ube2e2.L antikoerper, ube2e2 antikoerper, Ube2e2 antikoerper
    Hintergrund

    Synonyms: UB2E2_HUMAN, UBC4/5 homolog yeast, UBCH 8, UbcH8, Ube2e2, Ubiquitin carrier protein E2, Ubiquitin conjugating enzyme E2 E2, Ubiquitin conjugating enzyme E2E 2 homologous to yeast UBC4/5, Ubiquitin conjugating enzyme E2E 2 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2E 2, Ubiquitin protein ligase E2, Ubiquitin-conjugating enzyme E2 E2, Ubiquitin-protein ligase E2.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme. The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex. The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, thereby targeting that substrate for degradation. A wide range of enzymes facilitate this proteolytic ubiquitin pathway, one of which is UBE2E2 (also known as UBCH8 in human), which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, thereby playing an important role in protein degradation.

    Gen-ID
    7325
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