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UFD1L Antikörper (AbBy Fluor® 594)

UFD1L Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2807379
  • Target Alle UFD1L Antikörper anzeigen
    UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
    Reaktivität
    • 44
    • 31
    • 30
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 4
    Kaninchen
    Klonalität
    • 39
    • 5
    Polyklonal
    Konjugat
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UFD1L Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 36
    • 12
    • 10
    • 9
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UFD1L
    Isotyp
    IgG
    Top Product
    Discover our top product UFD1L Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
    Andere Bezeichnung
    UFD1L (UFD1L Produkte)
    Synonyme
    UFD1 antikoerper, Ufd1 antikoerper, ufd1 antikoerper, wu:fc55f04 antikoerper, zgc:92341 antikoerper, Ufd1l antikoerper, ubiquitin recognition factor in ER associated degradation 1 antikoerper, ubiquitin recognition factor in ER-associated degradation 1 antikoerper, ubiquitin fusion degradation 1 like (yeast) antikoerper, ubiquitin recognition factor in ER associated degradation 1 S homeolog antikoerper, ubiquitin fusion degradation protein 1 homolog antikoerper, Ubiquitin Fusion Degradation (yeast UFD homolog) antikoerper, UFD1 antikoerper, Ufd1 antikoerper, UFD1L antikoerper, ufd1.S antikoerper, ufd1l antikoerper, ufd1 antikoerper, EHI_125920 antikoerper, LOC100166745 antikoerper, LOC100635687 antikoerper, LOC100648660 antikoerper, ufd-1 antikoerper
    Hintergrund

    Synonyms: UB fusion protein 1, Ubiquitin fusion degradation 1 like yeast, Ubiquitin fusion degradation 1 like, Ubiquitin fusion degradation protein 1 homolog, UFD1, UFD1L.

    Background: UFD1L is a member of the UFD1 family of proteins and is a component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. This complex, also containing UFD1L, VCP and NPLOC4, binds ubiquitinated proteins and is required for the export of misfolded proteins from the ER to the cytoplasm for disposal. The NPLOC4-UFD1L-VCP complex also regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. UFD1L gene hemizygosity is the cause of some developmental defects including DiGeorge syndrome (DGS), velo-cardio-facial syndrome (VCFS) and Opitz G/BBB syndrome. UFD1L has 2 named isoforms produced by alternative splicing.

    Gen-ID
    7353
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