APIP Antikörper (AA 151-242) (AbBy Fluor® 594)
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- Target Alle APIP Antikörper anzeigen
- APIP (APAF1 Interacting Protein (APIP))
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Bindungsspezifität
- AA 151-242
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APIP Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human APIP
- Isotyp
- IgG
- Top Product
- Discover our top product APIP Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- APIP (APAF1 Interacting Protein (APIP))
- Andere Bezeichnung
- Apaf1 Interacting Protein (APIP Produkte)
- Synonyme
- APIP2 antikoerper, CGI29 antikoerper, MMRP19 antikoerper, dJ179L10.2 antikoerper, hAPIP antikoerper, CGI-29 antikoerper, Mmrp19 antikoerper, RGD1564562 antikoerper, zgc:103619 antikoerper, APAF1 interacting protein antikoerper, APAF1 interacting protein S homeolog antikoerper, APIP antikoerper, Apip antikoerper, apip antikoerper, apip.S antikoerper
- Hintergrund
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Synonyms: MTNB_HUMAN, Apaf1 Interacting Protein, APIP2, CG129, CGI 29, MMRP19, MTRu 1 P dehydratase, Probable methylthioribulose 1 phosphate dehydratase.
Background: The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.
- Gen-ID
- 51074
- Pathways
- Methionine Biosynthetic Process
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