APBB2 Antikörper (AA 251-350) (AbBy Fluor® 594)
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- Target Alle APBB2 Antikörper anzeigen
- APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))
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Bindungsspezifität
- AA 251-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APBB2 Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human APBB2
- Isotyp
- IgG
- Top Product
- Discover our top product APBB2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))
- Andere Bezeichnung
- APBB2/FE65L1 (APBB2 Produkte)
- Synonyme
- FE65L antikoerper, FE65L1 antikoerper, 2310007D03Rik antikoerper, Rirl1 antikoerper, TR2L antikoerper, Zfra antikoerper, RGD1562438 antikoerper, APBB2 antikoerper, fe65l antikoerper, fe65l1 antikoerper, DKFZp469I236 antikoerper, si:ch211-201g8.2 antikoerper, amyloid beta precursor protein binding family B member 2 antikoerper, amyloid beta (A4) precursor protein-binding, family B, member 2 antikoerper, amyloid beta (A4) precursor protein-binding, family B, member 2b antikoerper, APBB2 antikoerper, Apbb2 antikoerper, apbb2 antikoerper, apbb2b antikoerper
- Hintergrund
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Synonyms: Amyloid beta A4 precursor protein-binding, family B, member 2 Fe65 like, Amyloid beta A4 precursor protein binding family B member 2, Amyloid beta A4 precursor protein-binding family B member 2, APBB 2, APBB2, APBB2_HUMAN, Fe65 like 1, Fe65 like, Fe65 like protein, FE65L 1, FE65L, FE65L1, Protein Fe65-like 1, Rirl 1, Rirl1, TR2 L, TR2L, Zfra, Zinc finger like protein.
Background: Fe65L is a 758 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the -Amyloid precursor protein, Fe65L is thought to modulate the internalization and, therefore, the accessibility and function of -Amyloid. Via its ability to control the intracellular accumulation of -Amyloid, Fe65L is thought to play a role in the pathogenesis of Alzheimer's disease. Multiple isoforms of Fe65L exist due to alternative splicing events. The gene encoding Fe65L maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
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