CEP57 Antikörper (AA 51-150) (AbBy Fluor® 594)
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- Target Alle CEP57 Antikörper anzeigen
- CEP57 (Centrosomal Protein 57kDa (CEP57))
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Bindungsspezifität
- AA 51-150
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CEP57 Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CEP57
- Isotyp
- IgG
- Top Product
- Discover our top product CEP57 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CEP57 (Centrosomal Protein 57kDa (CEP57))
- Andere Bezeichnung
- CEP57 (CEP57 Produkte)
- Synonyme
- 3110002L15RIK antikoerper, CEP57 antikoerper, cep57r antikoerper, xCep57 antikoerper, c6orf182 antikoerper, 3110002l15rik antikoerper, RGD1309884 antikoerper, 3110002L15Rik antikoerper, 4921510P06Rik antikoerper, 4931428M20Rik antikoerper, AI467480 antikoerper, Tsp57 antikoerper, mKIAA0092 antikoerper, MVA2 antikoerper, PIG8 antikoerper, TSP57 antikoerper, centrosomal protein 57 antikoerper, centrosomal protein 57kDa-like 1 antikoerper, CEP57 antikoerper, cep57l1 antikoerper, Cep57 antikoerper
- Hintergrund
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Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57.
Background: CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.
- Pathways
- M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
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