Cyclic GMP Antikörper (AbBy Fluor® 594)
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- Target Alle Cyclic GMP (cGMP) Antikörper anzeigen
- Cyclic GMP (cGMP)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclic GMP Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Spezifität
- Due to the fact that BSA is used as the carrier, this antibody will cross-react with Albumin.
- Kreuzreaktivität
- Ratte
- Kreuzreaktivität (Details)
- cGMP
- Aufreinigung
- Purified by Protein A.
- Immunogen
- OVA conjugated cGMP
- Isotyp
- IgG
- Top Product
- Discover our top product cGMP Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Cyclic GMP (cGMP)
- Andere Bezeichnung
- cGMP (cGMP Produkte)
- Substanzklasse
- Chemical
- Hintergrund
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Synonyms: Cyclic GMP, Cyclic guanosine monophosphate, Guanosine 3 5 Cyclic Monophosphate.
Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
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