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CRTAP Antikörper (AA 201-300) (AbBy Fluor® 594)

CRTAP Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2811969
  • Target Alle CRTAP Antikörper anzeigen
    CRTAP (Cartilage Associated Protein (CRTAP))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 41
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 41
    • 1
    Kaninchen
    Klonalität
    • 41
    • 1
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRTAP Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 41
    • 19
    • 12
    • 12
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CRTAP
    Isotyp
    IgG
    Top Product
    Discover our top product CRTAP Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CRTAP (Cartilage Associated Protein (CRTAP))
    Andere Bezeichnung
    CRTAP (CRTAP Produkte)
    Synonyme
    zgc:85621 antikoerper, wu:fb47h01 antikoerper, CASP antikoerper, LEPREL3 antikoerper, OI7 antikoerper, 5730529N23Rik antikoerper, Leprel3 antikoerper, RGD1565180 antikoerper, cartilage associated protein antikoerper, cartilage-associated protein antikoerper, crtap antikoerper, CRTAP antikoerper, LOC5574430 antikoerper, CpipJ_CPIJ013810 antikoerper, Crtap antikoerper
    Hintergrund

    Synonyms: Cartilage associated protein, LEPREL3, leprecan-like 3, CASP, CRTAP_HUMAN.

    Background: CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.

    Gen-ID
    10491
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