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EMP2 Antikörper (AA 65-167) (AbBy Fluor® 594)

EMP2 Reaktivität: Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2812777
  • Target Alle EMP2 Produkte
    EMP2 (Epithelial Membrane Protein 2 (EMP2))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 8
    • 4
    • 2
    AA 65-167
    Reaktivität
    • 18
    • 15
    • 14
    • 1
    Ratte
    Wirt
    • 44
    Kaninchen
    Klonalität
    • 44
    Polyklonal
    Konjugat
    • 12
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EMP2 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 33
    • 19
    • 18
    • 12
    • 12
    • 8
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EMP2
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EMP2 (Epithelial Membrane Protein 2 (EMP2))
    Andere Bezeichnung
    EMP2 (EMP2 Produkte)
    Synonyme
    MGC52916 antikoerper, MGC130799 antikoerper, MGC69514 antikoerper, emp2 antikoerper, XMP antikoerper, epithelial membrane protein 2 L homeolog antikoerper, epithelial membrane protein 2 antikoerper, emp2.L antikoerper, emp2 antikoerper, EMP2 antikoerper, Emp2 antikoerper
    Hintergrund

    Synonyms: EMP-2, EMP2, EMP2_HUMAN, Epithelial membrane protein 2, Protein XMP.

    Background: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.

    Gen-ID
    2013
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