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EN1 Antikörper (AA 351-392) (AbBy Fluor® 594)

EN1 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2812783
  • Target Alle EN1 Antikörper anzeigen
    EN1 (Engrailed Homeobox 1 (EN1))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 351-392
    Reaktivität
    • 30
    • 19
    • 18
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 35
    • 1
    Kaninchen
    Klonalität
    • 34
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EN1 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 25
    • 13
    • 12
    • 12
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EN1/Engrailed 1
    Isotyp
    IgG
    Top Product
    Discover our top product EN1 Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EN1 (Engrailed Homeobox 1 (EN1))
    Andere Bezeichnung
    EN1/Engrailed 1 (EN1 Produkte)
    Synonyme
    EN1 antikoerper, En-1 antikoerper, Mo-en.1 antikoerper, ENG-1 antikoerper, en-1 antikoerper, en1 antikoerper, eng1 antikoerper, zgc:100771 antikoerper, en1-A antikoerper, engrailed-1 antikoerper, xen1 antikoerper, Gg-En-1 antikoerper, en-3 antikoerper, engrailed antikoerper, engrailed homeobox 1 antikoerper, engrailed 1 antikoerper, engrailed homeobox 1a antikoerper, engrailed homeobox 1 S homeolog antikoerper, EN1 antikoerper, En1 antikoerper, en1a antikoerper, en1.S antikoerper
    Hintergrund

    Synonyms: En 1, EN1, Engrailed 1, Engrailed, Engrailed homeobox 1, Engrailed homolog 1, HME1_HUMAN, Homeobox protein en-1, Homeobox protein engrailed 1, Homeobox protein engrailed-1, Hu-En-1, Mo-en.1.

    Background: The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson?s disease.

    Gen-ID
    2019
    UniProt
    Q05925
    Pathways
    Dopaminergic Neurogenesis
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