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EN2 Antikörper (AA 281-333) (AbBy Fluor® 594)

EN2 Reaktivität: Human, Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2812784
  • Target Alle EN2 Antikörper anzeigen
    EN2 (Engrailed Homeobox 2 (EN2))
    Bindungsspezifität
    • 18
    • 14
    • 13
    • 5
    • 1
    AA 281-333
    Reaktivität
    • 59
    • 30
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 56
    • 2
    • 1
    Kaninchen
    Klonalität
    • 57
    • 2
    Polyklonal
    Konjugat
    • 21
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EN2 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 48
    • 28
    • 12
    • 12
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EN2/Engrailed 2
    Isotyp
    IgG
    Top Product
    Discover our top product EN2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EN2 (Engrailed Homeobox 2 (EN2))
    Andere Bezeichnung
    EN2/Engrailed 2 (EN2 Produkte)
    Synonyme
    EN2 antikoerper, en antikoerper, en2 antikoerper, BB131122 antikoerper, En-2 antikoerper, RGD1561842 antikoerper, Gg-En-2 antikoerper, engrailed homeobox 2 antikoerper, engrailed homeobox antikoerper, engrailed 2 antikoerper, EN2 antikoerper, en antikoerper, En2 antikoerper
    Hintergrund

    Synonyms: Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2, EN2

    Background: The engrailed-2 gene, EN2, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homologs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expression of a-synuclein, a gene that is genetically linked to Parkinson?s disease. During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region. EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia.

    Gen-ID
    2020
    UniProt
    P19622
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